| Choldrith | 3 | Monstrosity | Medium | 15 | 66 | | chaotic evil | | Volo's Guide to Monsters | | | | | | |
| Chuul | 4 | Aberration | Large | 16 | 93 | swim | chaotic evil | | Monster Manual (SRD) | 19 | 10 | 16 | 5 | 11 | 5 |
| Clay golem | 9 | Construct | Large | 14 | 133 | | unaligned | | Monster Manual (SRD) | 20 | 9 | 18 | 3 | 8 | 1 |
| Cloaker | 8 | Aberration | Large | 14 | 78 | fly | chaotic neutral | | Monster Manual (SRD) | 17 | 15 | 12 | 13 | 12 | 14 |
| Cloud giant | 9 | Giant | Huge | 14 | 200 | | neutral good | | Monster Manual (SRD) | 27 | 10 | 22 | 12 | 16 | 16 |
| Cloud giant smiling one | 11 | Giant (cloud giant) | Huge | 15 | 262 | | chaotic neutral | | Volo's Guide to Monsters | | | | | | |
| Cockatrice | 0.5 | Monstrosity | Small | 11 | 27 | fly | unaligned | | Monster Manual (SRD) | 6 | 12 | 12 | 2 | 13 | 5 |
| Commoner | 0 | Humanoid (any race) | Medium | 10 | 4 | | any alignment | | Monster Manual (SRD) | 10 | 10 | 10 | 10 | 10 | 10 |
| Conjurer | 6 | Humanoid (any race) | Medium | 12 | 40 | | any alignment | | Volo's Guide to Monsters | | | | | | |
| Constrictor snake | 0.25 | Beast | Large | 12 | 13 | swim | unaligned | | Monster Manual (SRD) | 15 | 14 | 12 | 1 | 10 | 3 |
| Copper dragon wyrmling | 1 | Dragon | Medium | 16 | 22 | fly | chaotic good | | Monster Manual (SRD) | 15 | 12 | 13 | 14 | 11 | 13 |
| Corpse flower | 8 | Plant | Large | 12 | 127 | | chaotic evil | | Mordenkainen's Tome of Foes | | | | | | |
| Couatl | 4 | Celestial | Medium | 19 | 97 | fly | lawful good | | Monster Manual (SRD) | 16 | 20 | 17 | 18 | 20 | 18 |
| Cow | 0.25 | Beast | Large | 10 | 15 | | unaligned | | Volo's Guide to Monsters | 18 | 10 | 14 | 2 | 10 | 4 |
| Crab | 0 | Beast | Tiny | 11 | 2 | swim | unaligned | | Monster Manual (SRD) | 2 | 11 | 10 | 1 | 8 | 2 |
| Crag cat | 1 | Beast | Large | 13 | 34 | | unaligned | | Adventures (Storm King's Thunder) | | | | | | |
| Cranium rat | 0 | Beast | Tiny | 12 | 2 | | lawful evil | | Volo's Guide to Monsters | | | | | | |
| Crawling claw | 0 | Undead | Tiny | 12 | 2 | | neutral evil | | Monster Manual (BR) | 13 | 14 | 11 | 5 | 10 | 4 |
| Crocodile | 0.5 | Beast | Large | 12 | 19 | swim | unaligned | | Monster Manual (SRD) | 15 | 10 | 13 | 2 | 10 | 5 |
| Crokek toeck | 14 | Fiend (demon) | Gargantuan | 15 | 297 | swim | chaotic evil | | Adventures (Descent into Avernus) | | | | | | |
| Cult fanatic | 2 | Humanoid (any race) | Medium | 13 | 33 | | any non-good alignment | | Monster Manual (SRD) | 11 | 14 | 12 | 10 | 13 | 14 |
| Cultist | 0.12 | Humanoid (any race) | Medium | 12 | 9 | | any non-good alignment | | Monster Manual (SRD) | 11 | 12 | 10 | 10 | 11 | 10 |
| Cyclops | 6 | Giant | Huge | 14 | 138 | | chaotic neutral | | Monster Manual (SRD) | 22 | 11 | 20 | 8 | 6 | 10 |
| Dao | 11 | Elemental | Large | 18 | 187 | fly | neutral evil | | Monster Manual (BR) | 23 | 12 | 24 | 12 | 13 | 14 |
| Darkling | 0.5 | Fey | Small | 14 | 13 | | chaotic neutral | | Volo's Guide to Monsters | | | | | | |